Phenotypic differentiation of Streptococcus pyogenes populations is induced by recombination-driven gene-specific sweeps.

doi:10.1038/srep36644

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Article

Phenotypic differentiation of Streptococcus pyogenes populations is induced by recombination-driven gene-specific sweeps.

Scientific reports - 8 Nov 2016

Bao Yun-Juan, Shapiro B Jesse, Lee Shaun W, Ploplis Victoria A, Castellino Francis J

Abstract excerpt

Genomic recombination plays an important role in driving adaptive evolution and population differentiation in bacteria. However, controversy exists as to the effects of recombination on population diversity and differentiation, i.e., recombination is frequent enough to sweep through the population at selected gene loci (gene-specific sweeps), or the recombination rate is low without interfering genome-wide...

Topics

Genetic Loci
Genome, Bacterial
Humans
Polymorphism, Single Nucleotide
Recombination, Genetic
Streptococcus pyogenes

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PMID: 27821851
DOI: 10.1038/srep36644
PMCID: PMC5099688

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