Article
Polymorphism, genetic exchange and intragenic recombination of the aureolysin gene among Staphylococcus aureus strains.
BMC microbiology - 29 Jul 2008
Sabat Artur J, Wladyka Benedykt, Kosowska-Shick Klaudia, Grundmann Hajo, van Dijl Jan Maarten, Kowal Julia, Appelbaum Peter C, Dubin Adam, Hryniewicz Waleria
Abstract excerpt
BACKGROUND: Staphylococcus aureus expresses several proteases, which are thought to contribute to the virulence of this bacterium. Here we focus on aureolysin, the major thermolysin-like metalloprotease. Despite the importance of aureolysin in the physiology and pathogenesis of S. aureus, relatively little information was so far available concerning the aur gene diversity and mobility within and between the major...
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