The alpha 6A beta 1 and alpha 6B beta 1 integrin variants signal differences in the tyrosine phosphorylation of paxillin and other proteins.

doi:10.1074/jbc.270.40.23648

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Article

The alpha 6A beta 1 and alpha 6B beta 1 integrin variants signal differences in the tyrosine phosphorylation of paxillin and other proteins.

The Journal of biological chemistry - 6 Oct 1995

Shaw L M, Turner C E, Mercurio A M

Abstract excerpt

Integrin receptors can mediate transmembrane signaling in response to ligand binding. To further examine the role of the integrin alpha subunit in these signaling functions, we assessed the contribution of the alpha 6 cytoplasmic domain variants to the signaling properties of the alpha 6 beta 1 integrin using P388D1 cells that had been transfected with either the alpha 6A or the alpha 6B cDNA. The alpha 6A beta 1...

Topics

Animals
Cell Adhesion Molecules
Cell Line
Cytoplasm
Cytoskeletal Proteins
Genetic Variation
Humans
Integrin alpha6beta1
Integrins
Laminin
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Paxillin

Phosphoproteins

Phosphorylation

Proteins

Signal Transduction

Transfection

Tyrosine

Source

Open in PubMed

Identifiers

PMID: 7559532
DOI: 10.1074/jbc.270.40.23648

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7559532-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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