Cell type-specific integrin variants with alternative alpha chain cytoplasmic domains.

doi:10.1073/pnas.88.22.10183

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Article

Cell type-specific integrin variants with alternative alpha chain cytoplasmic domains.

Proceedings of the National Academy of Sciences of the United States of America - 15 Nov 1991

Tamura R N, Cooper H M, Collo G, Quaranta V

Abstract excerpt

The integrin heterodimers composed of the alpha 6 subunit with the beta 1 or beta 4 subunit (alpha 6 beta 1 and alpha 6 beta 4) are receptors for laminin and basement membrane components, respectively. The alpha 3 beta 1 integrin recognizes laminin, collagen, fibronectin, or epiligrin. We report the identification of structural variants (A and B) of the alpha 6 and alpha 3 subunits, containing distinct...

Topics

Amino Acid Sequence
Animals
Base Sequence
Cell Line
Cloning, Molecular
Cricetinae
Cytoplasm
Gene Expression
Genetic Variation
Humans
Immunoblotting

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Integrins

Macromolecular Substances

Molecular Sequence Data

Oligodeoxyribonucleotides

Polymerase Chain Reaction

RNA, Messenger

Sequence Homology, Nucleic Acid

Source

Open in PubMed Open full text

Identifiers

PMID: 1946438
DOI: 10.1073/pnas.88.22.10183
PMCID: PMC52892

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1946438-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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