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Article

Transcriptional Regulation of the Human GLUT4 Gene Promoter in Diabetic Transgenic Mice

1 Oct 1995

Abstract excerpt

We previously reported that 2400 base pairs (bp) of 5'-flanking DNA is sufficient for tissue-specific and hormonal/metabolic regulation of the human GLUT4 gene in transgenic mice (Liu, M.-L., Olson, A. L., Moye-Rowley, W. S., Buse, J. B., Bell, G. I., and Pessin, J. E. (1992) J. Biol. Chem. 267, 11673-11676). To further define the DNA sequences required for GLUT4 expression, we generated transgenic mice carrying...

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PMID: 7559512
DOI: 10.1074/jbc.270.40.23491

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