Article
Serologic subtyping of HLA-DR8 by means of the cytotoxic human monoclonal antibody 5643.
Human immunology - 1 Jul 1995
Viken H D, Thoresen A B, Knutsen I, Thorsby E, Hansen T
Abstract excerpt
EBV-transformed B cells from a multiparous woman with anti-HLA antibodies were hybridized with CB-F7 heteromyeloma cells. The resulting hybridoma produced the cytotoxic human IgM(kappa) mAb 5643. Testing of the hybridoma supernatant against HLA homozygous cell lines demonstrated positive reaction...
Topics
- Alleles
- Amino Acid Sequence
- Antibodies, Monoclonal
- Arthritis, Juvenile
- Cytotoxicity Tests, Immunologic
- Female
- HLA-D Antigens
- HLA-DR Antigens
- HLA-DR Serological Subtypes
- Histocompatibility Testing
- Humans
- Hybridomas
- Immunoglobulin M
- Molecular Sequence Data
- Norway
- Tumor Cells, Cultured
- White People