Article
Quantitative expression of epitopes defined by murine monoclonal antibodies on DR molecules from different HLA haplotypes.
Bioscience reports - 1 Jan 2000
Letarte M, Addis J, Iturbe S, Petsche D
Abstract excerpt
Monoclonal antibodies 50D6 and 21r5, reactive with human class II molecules, were analyzed quantitatively by flow cytometry and cellular radioimmunoassay for their binding to cells of different HLA-DR types. Monoclonal antibody 50D6 bound equally to cells of all DR types tested except DR7, where...
Topics
- Alleles
- Animals
- Antibodies, Monoclonal
- Cell Line
- Cell Membrane
- Epitopes
- Flow Cytometry
- Genes, MHC Class II
- Genetic Linkage
- HLA-DR Antigens
- HLA-DR7 Antigen
- Histocompatibility Antigens Class II
- Humans
- Mice
- Phenotype
- Radioimmunoassay