Article
Quantitative expression of epitopes defined by murine monoclonal antibodies on DR molecules from different HLA haplotypes.
Bioscience reports - 1 Jan 2000
Letarte M, Addis J, Iturbe S, Petsche D
Abstract excerpt
Monoclonal antibodies 50D6 and 21r5, reactive with human class II molecules, were analyzed quantitatively by flow cytometry and cellular radioimmunoassay for their binding to cells of different HLA-DR types. Monoclonal antibody 50D6 bound equally to cells of all DR types tested except DR7, where no reactivity was observed. Monoclonal antibody 21r5 was reactive with all cells. However, the percentage of DR...
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