Article
A monoclonal antibody with specificity to the HLA-DR1 and -DR51 antigens.
Tissue antigens - 1 Aug 1993
Loh M T, Chan S H, Ren E C
Abstract excerpt
A monoclonal antibody 137BL7 raised against purified DR1 protein was shown to bind specifically to 5/5 DR1, 18/18 DR2 cells and 0/23 non-DR1,2 cells by cell-EIA. Further analysis by FACS using HLA-transfectants revealed that 137BL7 also bound specifically to the DRB5 transfectants in addition to...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Antibodies, Monoclonal
- Antibody Specificity
- Base Sequence
- Cell Line
- Cross Reactions
- Female
- HLA-DR Antigens
- HLA-DR1 Antigen
- HLA-DRB5 Chains
- Humans
- Hybridomas
- Mice
- Mice, Inbred BALB C
- Molecular Sequence Data
- Sequence Alignment
