Article
Molecular analysis of an XY mare with gonadal dysgenesis.
Hereditas - 1 Jan 1995
Pailhoux E, Cribiu E P, Parma P, Cotinot C
Abstract excerpt
In this study, cytogenetic analysis of an infertile mare revealed a 64, XY karyotype. The XY sex-reversed animal had a female phenotype with gonadal dysgenesis. Using Southern blot analysis, we tested for the presence of two Y-specific genes SRY and ZFY by using DNA isolated from peripheral blood leukocytes. The results showed that at least the DNA-binding domain of the SRY gene was deleted from the Y chromosome...
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