Article
XY (SRY-positive) Ovarian Disorder of Sex Development in Cattle.
Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation - 1 Jan 2018
De Lorenzi Lisa, Arrighi Silvana, Rossi Elena, Grignani Pierangela, Previderè Carlo, Bonacina Stefania, Cremonesi Fausto, Parma Pietro
Abstract excerpt
In mammals, the sex of the embryo depends on the SRY gene. In the presence of at least one intact and functional copy of this genetic factor (XY embryo) undifferentiated gonads will develop as testicles that subsequently determine the male phenotype. When this factor is not present, i.e., in subjects with 2 X chromosomes, an alternative pathway induces the development of ovaries, hence a female phenotype. In this...
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