Article
Equine disorders of sexual development in 17 mares including XX, SRY-negative, XY, SRY-negative and XY, SRY-positive genotypes.
Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation - 1 Jan 2011
Villagómez D A F, Lear T L, Chenier T, Lee S, McGee R B, Cahill J, Foster R A, Reyes E, St John E, King W A
Abstract excerpt
We described the clinical, cytogenetic and molecular findings of 17 clinical equine cases presented for abnormal sexual development and infertility. Six horses with an enlarged clitoris had an XX, SRY-negative genotype, which displayed male-like behavior (adult individuals). Bilateral ovotestes were noted in 2 of those cases, while another case showed increased levels of circulating testosterone. Six horses with...
Topics
- Animals
- Chromosome Banding
- Disorders of Sex Development
- Female
- Gene Deletion
- Genes, sry
- Genitalia
- Horse Diseases
- Horses
- In Situ Hybridization, Fluorescence
- Male
- Phenotype
- Sex Determination Processes