Lack of mutational alteration in the conserved regions of ZFY and SRY genes of 46,XY females with gonadal dysgenesis.

doi:10.1093/oxfordjournals.humrep.a138027

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Article

Lack of mutational alteration in the conserved regions of ZFY and SRY genes of 46,XY females with gonadal dysgenesis.

Human reproduction (Oxford, England) - 1 Feb 1993

Pao C C, Kao S M, Hor J J, Chang S Y

Abstract excerpt

To further our understanding of the mechanism of action of regulatory and structural genes involved in human sex determination, we have examined three sex-reversed 46,XY females and two of their normal fathers for any mutational alteration in ZFY and SRY genes, using polymerase chain reaction and...

Topics

Base Sequence
Female
Gonadal Dysgenesis, 46,XY
Humans
Molecular Sequence Data
Mutation
Phenotype
Polymorphism, Genetic

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