Article
Relationships among in vitro mutagenicity assays: quantitative vs. qualitative test results.
Environmental and molecular mutagenesis - 1 Jan 1995
Benigni R, Andreoli C, Giuliani A
Abstract excerpt
In previous investigations, we studied the relationships between the profiles of the qualitative responses of in vitro short-term tests (mutation in Salmonella typhimurium, chromosomal aberrations in CHO cells, sister chromatid exchanges in CHO cells, and mutation in mouse lymphoma cells) and common sets of chemicals. In this paper, we address the study of the quantitative responses (potency). We show that two...
Topics
- Analysis of Variance
- Animals
- CHO Cells
- Chromosome Aberrations
- Cluster Analysis
- Cricetinae
- Lymphoma
- Mice
- Mutagenicity Tests
- Mutagens
- Mutation
- Salmonella typhimurium