Prediction of cancer potency using a battery of mutation and toxicity data.

doi:10.1093/mutage/5.3.213

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Article

Prediction of cancer potency using a battery of mutation and toxicity data.

Mutagenesis - 1 May 1990

Travis C C, Saulsbury A W, Pack S A

Abstract excerpt

Correlations between the carcinogenic potencies of 146 known mouse carcinogens and potency estimates determined from (i) Ames test results, (ii) a battery of mutation test results, and (iii) a battery of mutation and toxicity data are presented. The lowest correlation was found using Salmonella m...

Topics

Animals
Carcinogenicity Tests
Carcinogens
Liver Neoplasms
Lung Neoplasms
Mice
Mutagenicity Tests
Mutagens
Mutation
Neoplasms, Experimental

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