Article
Goosecoid and cerberus-like do not interact during mouse embryogenesis.
The International journal of developmental biology - 1 Mar 2002
Borges Ana C, Marques Sara, Belo José A
Abstract excerpt
Mouse Cerberus-like (Cer-l) is a neural inducer molecule, capable of inhibiting Nodal and BMP-4 signals in the extracelular space. The cer-l expression domain in the Anterior Visceral Endoderm (AVE) and prechordal plate, tissues involved in head induction and patterning, respectively, suggested a role for this gene in head formation. However, animals homozygous for the cer-l null allele failed to show any...
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