Attenuated typhoid vaccine Salmonella typhi Ty21a: fingerprinting and quality control.

doi:10.1099/13500872-141-8-1993

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Article

Attenuated typhoid vaccine Salmonella typhi Ty21a: fingerprinting and quality control.

Microbiology (Reading, England) - 1 Aug 1995

McKenna Alison J, Bygraves Jane A, Maiden Martin C J, Feavers Ian M

Abstract excerpt

Live attenuated vaccines, developed with molecular genetical techniques, require new approaches for their quality control. To develop novel quality control tests that enhanced and extended existing procedures, the attenuated vaccine strain Salmonella typhi Ty21a and its parent strain Ty2 were cha...

Topics

Amino Acid Sequence
Base Sequence
Blotting, Southern
Carbohydrate Epimerases
DNA, Bacterial
Electrophoresis, Gel, Pulsed-Field
Enterobacteriaceae
Galactose
Genome, Bacterial
Molecular Sequence Data
Mutation
Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Restriction Fragment Length

Quality Control

Salmonella typhi

Sequence Homology, Nucleic Acid

UDPglucose 4-Epimerase

Vaccines, Attenuated

Source

Open in PubMed

Identifiers

PMID: 7551062
DOI: 10.1099/13500872-141-8-1993

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7551062-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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