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Article

Impulsiveness as the intermediate link between the dopamine receptor D2 gene and alcohol dependence

1 Jun 2003

Abstract excerpt

OBJECTIVES: Reinforcement and reward processes have been proposed as being an intermediate link between the risk for alcohol dependence and the gene coding for the dopamine receptor D2 (DRD2). This hypothesis remains open to speculation, and personality traits such as impulsiveness, a core dimension in addictive disorders, should also be taken into account. For instance, recent evidence in rats showed that DRD2...

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PMID: 12782972
DOI: 10.1097/01.ypg.0000066963.66429.00

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