Article
Glutathione S-transferase mu genotype, diet, and smoking as determinants of sister chromatid exchange frequency in lymphocytes.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jan 2000
Cheng T J, Christiani D C, Xu X, Wain J C, Wiencke J K, Kelsey K T
Abstract excerpt
Polymorphisms in inherited metabolic traits and intake of dietary antioxidants have been reported to be associated with risk for the development of lung cancer in smokers. This increased risk of lung cancer is presumably attributable to the accumulation of DNA damage. We conducted a study to inve...
Topics
- Age Factors
- Analysis of Variance
- Antioxidants
- Base Sequence
- Diet
- Female
- Genotype
- Glutathione Transferase
- Humans
- Lung Neoplasms
- Lymphocytes
- Male
- Middle Aged
- Molecular Sequence Data
- Pedigree
- Risk Factors
- Sex Factors
- Sister Chromatid Exchange