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Article

Effects on sister chromatid exchange frequency of polymorphisms in DNA repair gene XRCC1 in smokers.

Mutation research - 26 Aug 2002

Lei Yu-Chen, Hwang Shing-jen, Chang Chuen-Chau, Kuo Hsen-Wen, Luo Jiin-Chyuan, Chang Ming J W, Cheng Tsun-Jen

Abstract excerpt

The association between metabolic polymorphisms and cigarette smoking-induced cancers has been documented. However, the role of DNA repair polymorphism in carcinogenesis is less clear. To investigate if the polymorphisms of metabolic traits and DNA repair modulate smoking-related DNA damage, we used sister chromatid exchange (SCE) as a marker of genetic damage to explore the relationship of microsomal epoxide...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12160895
DOI: 10.1016/s1383-5718(02)00127-4

Genes

XRCC1
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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