Article
Allelic imbalance in gastric cancer: an affected site on chromosome arm 3p.
Genes, chromosomes & cancer - 1 Aug 1995
Schneider B G, Pulitzer D R, Brown R D, Prihoda T J, Bostwick D G, Saldivar V, Rodríguez-Martínez H A, Gutiérrez-Díaz M E, O'Connell P
Abstract excerpt
In order to detect regions of DNA containing tumor suppressor genes involved in the development of gastric cancer, we performed an allelotype study on 78 gastric adenocarcinomas from a population composed largely of Texan Hispanics and Anglos, two ethnic groups that have a ratio of incidence rates of gastric cancer of approximately 2:1. In total, 42 microsatellite markers were employed, which detected at least...
Topics
- Adenocarcinoma
- Alleles
- Chromosome Deletion
- Chromosomes, Human, Pair 3
- Genes, Tumor Suppressor
- Genetic Markers
- Humans
- Microsatellite Repeats
- Stomach Neoplasms