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Article

The prognostic significance of allelic imbalance at key chromosomal loci in oral cancer.

British journal of cancer - 1 Apr 1999

Partridge M, Emilion G, Pateromichelakis S, A'Hern R, Lee G, Phillips E, Langdon J

Abstract excerpt

Forty-eight primary oral squamous cell carcinomas (SCC) were screened for allelic imbalance (AI) at 3p24-26, 3p21, 3p13, 8p21-23, 9p21, 9q22 and within the Rb, p53 and DCC tumour suppressor genes. AI was detected at all TNM stages with stage 4 tumours showing significantly more aberrations than stage 1-3. A factional allelic loss (FAL) score was calculated for all tumours and a high score was associated with...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 10206299
DOI: 10.1038/sj.bjc.6690290
PMCID: PMC2362810

Genes

DCC
THRB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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