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Article

The role of fs(1)K10 in the localization of the mRNA of the TGF alpha homolog gurken within the Drosophila oocyte.

Mechanisms of development - 1 Jun 1995

Serano T L, Karlin-McGinness M, Cohen R S

Abstract excerpt

A critical step in Drosophila dorsoventral patterning is the movement of gurken mRNA from the anterior cortex of the oocyte to the oocyte's anterodorsal corner at stage 8 of oogenesis. Such movement is dependent on fs(1)K10. It has been proposed that fs(1)K10 mediates gurken mRNA movement by down-regulating gurken mRNA levels, thus ensuring that gurken mRNA does not saturate its receptors located in the oocyte's...

Topics

Animals
Cell Polarity
Down-Regulation
Drosophila
Drosophila Proteins
Female
Genes, Insect
Insect Hormones
Male
Mutation
Oocytes
Oogenesis

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PMID: 7547466
DOI: 10.1016/0925-4773(95)00363-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7547466-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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The role of fs(1)K10 in the localization of the mRNA of the TGF alpha homolog gurken within the Drosophila oocyte.PMID 7547466Read ↗

Evidence for a transport-trap mode of Drosophila melanogaster gurken mRNA localization.Semantic proximity Read ↗

The Drosophila dorsoventral patterning gene gurken produces a dorsally localized RNA and encodes a TGF alpha-like protein.Semantic proximity Read ↗

maelstrom is required for an early step in the establishment of Drosophila oocyte polarity: posterior localization of grk mRNA.Semantic proximity Read ↗

Evidence for a highly selective RNA transport system and its role in establishing the dorsoventral axis of the Drosophila egg.Semantic proximity Read ↗

Post-transcriptional regulation of gurken by encore is required for axis determination in Drosophila.Semantic proximity Read ↗

A regulatory function for K10 in the establishment of dorsoventral polarity in the Drosophila egg and embryo.Semantic proximity Read ↗

The dynamics of fluorescently labeled endogenous gurken mRNA in Drosophila.Semantic proximity Read ↗

The role of oocyte transcription, the 5'UTR, and translation repression and derepression in Drosophila gurken mRNA and protein localization.Semantic proximity Read ↗

The angle of the dorsoventral axis with respect to the anteroposterior axis in the Drosophila embryo is controlled by the distribution of gurken mRNA in the oocyte.Semantic proximity Read ↗

Requirement for the vasa RNA helicase in gurken mRNA localization.Semantic proximity Read ↗

An autoregulatory cascade of EGF receptor signaling patterns the Drosophila egg.Semantic proximity Read ↗

The relationship between ovarian and embryonic dorsoventral patterning in Drosophila.Semantic proximity Read ↗

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