Article
Modification of retroviral RNA by double-stranded RNA adenosine deaminase.
Journal of virology - 1 Sept 1995
Hajjar A M, Linial M L
Abstract excerpt
In this report, we describe a recombinant provirus generated during in vitro passage that contains a short region of adenosine-to-guanosine hypermutation. The hypermutated region is restricted to complementary sequences present in the recombinant provirus. We propose that a duplex was formed in the recombinant RNA prior to reverse transcription. This duplex was a substrate for double-stranded RNA adenosine...
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