Article
Modification of retroviral RNA by double-stranded RNA adenosine deaminase.
Journal of virology - 1 Sept 1995
Hajjar A M, Linial M L
Abstract excerpt
In this report, we describe a recombinant provirus generated during in vitro passage that contains a short region of adenosine-to-guanosine hypermutation. The hypermutated region is restricted to complementary sequences present in the recombinant provirus. We propose that a duplex was formed in t...
Topics
- Adenosine
- Adenosine Deaminase
- Animals
- Avian Sarcoma Viruses
- Base Sequence
- Cell Line
- DNA Primers
- Genes, env
- Genes, pol
- Guanosine
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Proviruses
- Quail
- RNA
- RNA, Antisense
- RNA, Viral