Article
HPRT mutations in lymphocytes from 1,3-butadiene-exposed workers in China.
Environmental health perspectives - 1 Feb 2008
Liu Shengxue, Ao Lin, Du Bing, Zhou Yanhong, Yuan Jian, Bai Yang, Zhou Ziyuan, Cao Jia
Abstract excerpt
BACKGROUND: 1,3-Butadiene (BD) is an important industrial chemical and an environmental and occupational pollutant. The carcinogenicity of BD in rodents has been proved, but its carcinogenic and mutagenic molecular mechanism(s) are not fully elucidated in humans. OBJECTIVES: In the present study, we compared the mutation frequencies and exon deletions of BD-exposed workers with that of control subjects in China...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
