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Article

Novel mutation in 16S rRNA associated with streptomycin dependence in Mycobacterium tuberculosis.

Antimicrobial agents and chemotherapy - 1 Mar 1995

Honoré N, Marchal G, Cole S T

Abstract excerpt

Molecular characterization of a streptomycin-dependent mutant of Mycobacterium tuberculosis revealed the presence of a novel mutation in the rrs gene encoding 16S rRNA. Insertion of an additional cytosine in the 530 loop of 16S rRNA, a region known to be involved in streptomycin susceptibility and resistance, was associated with streptomycin dependence.

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 7540819
DOI: 10.1128/AAC.39.3.769
PMCID: PMC162623

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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