Article
16S rRNA gene mutations associated with decreased susceptibility to tetracycline in Mycoplasma bovis.
Antimicrobial agents and chemotherapy - 1 Feb 2015
Amram E, Mikula I, Schnee C, Ayling R D, Nicholas R A J, Rosales R S, Harrus S, Lysnyansky I
Abstract excerpt
Mycoplasma bovis isolates with decreased susceptibilities to tetracyclines are increasingly reported worldwide. The acquired molecular mechanisms associated with this phenomenon were investigated in 70 clinical isolates of M. bovis. Sequence analysis of the two 16S rRNA-encoding genes (rrs3 and rrs4 alleles) containing the primary binding pocket for tetracycline (Tet-1 site) was performed on isolates with...
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