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Article

CSF-1 treatment promotes angiogenesis in the metaphysis of osteopetrotic (toothless, tl) rats.

Bone - 1 Mar 1995

Aharinejad S, Marks S C, Böck P, Mason-Savas A, MacKay C A, Larson E K, Jackson M E, Luftensteiner M, Wiesbauer E

Abstract excerpt

It has recently been shown that following treatment with colony-stimulating factor-1 (CSF-1) the osteopetrotic condition in toothless (tl) rats greatly improves and growth is accelerated. We have examined the effects of such treatment on the microvasculature of the distal femoral chondro-osseous...

Topics

Animals
Arterioles
Capillaries
Cartilage
Corrosion Casting
Endothelium, Vascular
Female
Femur
Macrophage Colony-Stimulating Factor
Male
Microscopy, Electron
Microscopy, Electron, Scanning

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Neovascularization, Pathologic

Osteopetrosis

Rats

Rats, Mutant Strains

Source

Identifiers

PMID: 7540405
DOI: 10.1016/8756-3282(94)00044-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7540405-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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CSF-1 treatment promotes angiogenesis in the metaphysis of osteopetrotic (toothless, tl) rats.PMID 7540405Read ↗

Colony-stimulating factor 1 when combined with parathyroid hormone or 1,25-dihydroxyvitamin D can produce osteoclasts in cultured neonatal metatarsals from toothless (tl-osteopetrotic) rats.Semantic proximity Read ↗

Administration of colony stimulating factor-1 corrects some macrophage, dental, and skeletal defects in an osteopetrotic mutation (toothless, tl) in the ratSemantic proximity Read ↗

The effects of colony-stimulating factor-1 (CSF-1) on the development of osteoclasts and their expression of tartrate-resistant acid phosphatase (TRAP) in toothless (tl-osteopetrotic) rats.Semantic proximity Read ↗

The biology and action of colony stimulating factor-1.Semantic proximity Read ↗

Abnormalities in bone cell function and endochondral ossification in the osteopetrotic toothless rat.Semantic proximity Read ↗

Vascular endothelial growth factor can substitute for macrophage colony-stimulating factor in the support of osteoclastic bone resorption.Semantic proximity Read ↗

Mutation of macrophage colony stimulating factor (Csf1) causes osteopetrosis in the tl rat.Semantic proximity Read ↗

Heterogeneity of colony stimulating factor-1 gene expression in the skeleton of four osteopetrotic mutations in rats and mice.Semantic proximity Read ↗

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