Article
The unc-8 and sup-40 genes regulate ion channel function in Caenorhabditis elegans motorneurons.
Genetics - 1 Mar 1995
Shreffler W, Magardino T, Shekdar K, Wolinsky E
Abstract excerpt
Two Caenorhabditis elegans genes, unc-8 and sup-40, have been newly identified, by genetic criteria, as regulating ion channel function in motorneurons. Two dominant unc-8 alleles cause motorneuron swelling similar to that of other neuronal types in dominant mutants of the deg-1 gene family, whic...
Topics
- Alleles
- Animals
- Base Sequence
- Caenorhabditis elegans
- Cell Nucleus
- Female
- Genes, Helminth
- Genes, Suppressor
- Genotype
- Ion Channels
- Male
- Masoprocol
- Molecular Sequence Data
- Motor Neurons
- Mutation
- Oocytes
- Phenotype
- Suppression, Genetic