Article
sup-9, sup-10, and unc-93 may encode components of a two-pore K+ channel that coordinates muscle contraction in Caenorhabditis elegans.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 8 Oct 2003
de la Cruz Ignacio Perez, Levin Joshua Z, Cummins Claudia, Anderson Philip, Horvitz H Robert
Abstract excerpt
Genetic studies of sup-9, unc-93, and sup-10 strongly suggest that these genes encode components of a multi-subunit protein complex that coordinates muscle contraction in Caenorhabditis elegans. We cloned sup-9 and sup-10 and found that they encode a two-pore K+ channel and a novel transmembrane protein, respectively. We also found that UNC-93 and SUP-10 colocalize with SUP-9 within muscle cells, and that UNC-93...
Topics
- Amino Acid Sequence
- Animals
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Cloning, Molecular
- Exons
- GABA Agonists
- GTPase-Activating Proteins
- Green Fluorescent Proteins
- Introns
- Luminescent Proteins
- Membrane Proteins