Article
Mobilized Peripheral Blood versus Cord Blood: Insight into the Distinct Role of Proinflammatory Cytokines on Survival, Clonogenic Ability, and Migration of CD34+ Cells.
Mediators of inflammation - 1 Jan 2018
Forte Dorian, Sollazzo Daria, Barone Martina, Allegri Marisole, di Martella Orsi Angela, Romano Marco, Sinigaglia Barbara, Auteri Giuseppe, Vianelli Nicola, Cavo Michele, Palandri Francesca, Catani Lucia
Abstract excerpt
Inflammation may play a role in cancer. However, the contribution of cytokine-mediated crosstalk between normal hemopoietic stem/progenitor cells (HSPCs) and their (inflammatory) microenvironment is largely elusive. Here we compared survival, phenotype, and function of neonatal (umbilical cord blood (CB)) and adult (normal G-CSF-mobilized peripheral blood (mPB)) CD34+ cells after in vitro exposure to combined...
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