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Article

Fusion of the <i>FUS</i> gene with <i>ERG</i> in acute myeloid leukemia with t(16;21)(p11;q22)

1 Dec 1994

Abstract excerpt

It has been shown that the gene ERG in 21q22 is rearranged in the t(16;21)(p11;q22) associated with acute myeloid leukemia (AML). ERG is a member of the ETS gene family and is fused with EWS in a subset of Ewing's sarcomas. EWS in 22q12 has a very high homology with FUS (also called TLS) in 16p11; the latter gene is rearranged in the t(12;16)(q13;p11) that characterizes myxoid liposarcoma. To investigate whether...

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Identifiers

PMID: 7533529
DOI: 10.1002/gcc.2870110408

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Related research

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Research trail→

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Fusion of the <i>FUS</i> gene with <i>ERG</i> in acute myeloid leukemia with t(16;21)(p11;q22)PMID 7533529Read ↗

Consistent detection of TLS/FUS-ERG chimeric transcripts in acute myeloid leukemia with t(16;21)(p11;q22) and identification of a novel transcript.Semantic proximity Read ↗

An ets-related gene, ERG, is rearranged in human myeloid leukemia with t(16;21) chromosomal translocation.Semantic proximity Read ↗

Molecular characteristic of acute leukemias with t(16;21)/FUS-ERG.Semantic proximity Read ↗

EWS-ERG fusion transcript produced by chromosomal insertion in a Ewing sarcoma.Semantic proximity Read ↗

TLS/FUS-ERG fusion gene in acute leukemia and myelodysplastic syndrome evolved to acute leukemia: report of six cases and a literature reviewSemantic proximity Read ↗

Gain of chromosome 21 or amplification of chromosome arm 21q is one mechanism for increased ERG expression in acute myeloid leukemia.Semantic proximity Read ↗

Acute myeloid leukemia with complex karyotypes and abnormal chromosome 21: Amplification discloses overexpression of <i>APP</i> , <i>ETS2</i> , and <i>ERG</i> genesSemantic proximity Read ↗

Fusion gene‐mediated truncation of <i>RUNX1</i> as a potential mechanism underlying disease progression in the 8p11 myeloproliferative syndromeSemantic proximity Read ↗

The Partner Gene of AML1 in t(16;21) Myeloid Malignancies Is a Novel Member of the MTG8(ETO) FamilySemantic proximity Read ↗

Novel <i>RUNX1‐PRDM16</i> fusion transcripts in a patient with acute myeloid leukemia showing t(1;21)(p36;q22)Semantic proximity Read ↗

Fusion of the <i>SEC31L1</i> and <i>ALK</i> genes in an inflammatory myofibroblastic tumorSemantic proximity Read ↗

Fusion of the <i>EWS</i> Gene to a DNA segment from 9q22‐31 in a human myxoid chondrosarcomaSemantic proximity Read ↗

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