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Article

Molecular characteristic of acute leukemias with t(16;21)/FUS-ERG.

Annals of hematology - 1 Jun 2018

Zerkalenkova Elena, Panfyorova Agnesa, Kazakova Anna, Baryshev Pavel, Shelihova Larisa, Kalinina Irina, Novichkova Galina, Maschan Michael, Maschan Aleksey, Olshanskaya Yulia

Abstract excerpt

T(16;21)(p11;q22)/FUS-ERG is a rare but recurrent translocation in acute leukemias and in some types of solid tumors. Due to multiple types of FUS-ERG transcripts, PCR-based minimal residual disease detection is impeded. In this study, we evaluated a cohort of pediatric patients with t(16;21)(p11;q22)/FUS-ERG and revealed fusion gene breakpoints. We implemented next-generation sequencing (NGS) on long PCR...

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Share to Chromosomes, Human, Pair 16
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to DNA (Cytosine-5-)-Methyltransferases

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Source

Identifiers

PMID: 29427188
DOI: 10.1007/s00277-018-3267-z

Genes

ERG
FUS
ASXL1
BCOR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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