Article
EWS-ERG fusion transcript produced by chromosomal insertion in a Ewing sarcoma.
Genes, chromosomes & cancer - 1 Mar 1997
Kaneko Y, Kobayashi H, Handa M, Satake N, Maseki N
Abstract excerpt
The EWS gene is fused in Ewing sarcoma-like tumors by a chromosomal translocation to one of the four ETS-family genes: FLI1, ERG, ETV1, and E1AF. The orientation of EWS and FLI1 on chromosomes 22 and 11, respectively, is 5' centromeric and 3' telomeric, whereas that of ERG on chromosome 21 is the...
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