Article
Genetic disorders of keratin: are scarring alopecias a sub-set?
Journal of dermatological science - 1 Jul 1994
Rothnagel J A, Longley M A, Holder R A, Bundman D S, Seki T, Bickenbach J R, Roop D R
Abstract excerpt
Recent advances have challenged the prevailing view that keratins are merely passive bystanders of keratinocyte biology. With the exciting discovery that three autosomal dominant genetic skin disorders, epidermolysis bullosa simplex (EBS), epidermolytic hyperkeratosis (EHK) and palmoplantar kerat...
Topics
- Alopecia
- Animals
- Disease Models, Animal
- Epidermis
- Humans
- Keratinocytes
- Keratins
- Mice
- Mice, Transgenic
- Molecular Structure
- Multigene Family
- Mutation