Keratin genes, epidermal differentiation and animal models for the study of human skin diseases.

doi:10.1042/bst0191112

Back to search

Article

Keratin genes, epidermal differentiation and animal models for the study of human skin diseases.

Biochemical Society transactions - 1 Nov 1991

Fuchs E

Abstract excerpt

The examples shown here illustrate the power of gene targeting to the epidermis as a means of developing animal models for the study of human skin diseases. In this short review, I have focused on contributions which stem predominantly from my own laboratory [31, 32, 34, 37, 47]. However, other l...

Topics

Animals
Disease Models, Animal
Humans
Keratins
Mice
Mice, Transgenic
Mutation
Skin
Skin Diseases
Transcription, Genetic
Transforming Growth Factor alpha

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.