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Article

Inducible mouse models for inherited skin diseases: implications for skin gene therapy.

Cells, tissues, organs - 1 Jan 2004

Arin Meral J, Roop Dennis R

Abstract excerpt

Stem cells are crucial for the formation and maintenance of tissues and organs. To understand the role of stem cells in the pathogenesis of mosaic skin disorders, we generated inducible mouse models for two autosomal dominant keratin disorders, epidermolytic hyperkeratosis (EHK) and epidermolysis bullosa simplex (EBS), that enable activation of the respective mutation in epidermal stem cells in a spatially and...

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Identifiers

PMID: 15388990
DOI: 10.1159/000079990

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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