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Article

A function for keratins and a common thread among different types of epidermolysis bullosa simplex diseases.

The Journal of cell biology - 1 Dec 1991

Coulombe P A, Hutton M E, Vassar R, Fuchs E

Abstract excerpt

Previously we demonstrated that transgenic mice expressing a mutant keratin in the basal layer of their stratified squamous epithelia exhibited a phenotype bearing resemblance to a subclass (Dowling Meara) of a heterogeneous group of human skin disorders known as epidermolysis bullosa simplex (EBS) (Vassar, R., P. A. Coulombe, L. Degenstein, K. Albers, E. Fuchs. 1991. Cell. 64:365-380.). The extent to which...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 1721910
DOI: 10.1083/jcb.115.6.1661
PMCID: PMC2289221

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Source receipt: pubmed, retrieved 7 Sept 2026.

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