Variability of EWS chimaeric transcripts in Ewing tumours: a comparison of clinical and molecular data.

doi:10.1038/bjc.1994.419

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Article

Variability of EWS chimaeric transcripts in Ewing tumours: a comparison of clinical and molecular data.

British journal of cancer - 1 Nov 1994

Zoubek A, Pfleiderer C, Salzer-Kuntschik M, Amann G, Windhager R, Fink F M, Koscielniak E, Delattre O, Strehl S, Ambros P F

Abstract excerpt

Ewing tumours (ET), including Ewing's sarcoma and peripheral primitive neuroectodermal tumour, are well characterised at the molecular level by a unique chromosomal rearrangement which fuses the EWS gene to one of two closely related ETS proto-oncogenes, FLI-1 or ERG. Expression of the resulting...

Topics

Adolescent
Adult
Base Sequence
Child
Child, Preschool
Chimera
Chromosomes, Human, Pair 22
Exons
Female
Gene Rearrangement
Genetic Variation
Humans
Karyotyping
Male
Molecular Sequence Data
Polymerase Chain Reaction

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PMID: 7524604
DOI: 10.1038/bjc.1994.419
PMCID: PMC2033557

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7524604-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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