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Article

[Molecular basis and clinical significance of HIV-1 resistance to nucleoside compounds].

Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie - 1 Mar 1995

Wainberg M A, Gu Z, Salomon H, Arts E J, Kleiman L, Parniak M A, Morin N

Abstract excerpt

The prolonged use of anti-viral nucleosides (ZDV, ddI, ddC) in HIV-infected patients has given rise to the isolation of viral variants that display resistance against these compounds. Tissue culture selection experiments, involving increasing concentrations of anti-viral compounds, have likewise been shown to select for drug-resistant strains of HIV. Cloning, sequencing and site-directed mutagenesis have shown...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 7540494

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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