Article
Effect of in ovo retinoic acid exposure on forebrain neural crest: in vitro analysis reveals up-regulation of N-CAM and loss of mesenchymal phenotype.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jun 1994
Shankar K R, Chuong C M, Jaskoll T, Melnick M
Abstract excerpt
In a prior study of in ovo exogenous retinoic acid (RA) exposure, we observed a prolonged expression of cell surface N-CAM in cranial neural crest (NC) cells exhibiting migratory failure. In the present studies, we employed an experimental strategy in which embryos were first exposed to exogenous RA in ovo and incubated for 45-60 hr; this was followed by extirpation and in vitro culturing of these same RA-exposed...
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