Article
Effect of in ovo retinoic acid exposure on forebrain neural crest: in vitro analysis reveals up-regulation of N-CAM and loss of mesenchymal phenotype.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jun 1994
Shankar K R, Chuong C M, Jaskoll T, Melnick M
Abstract excerpt
In a prior study of in ovo exogenous retinoic acid (RA) exposure, we observed a prolonged expression of cell surface N-CAM in cranial neural crest (NC) cells exhibiting migratory failure. In the present studies, we employed an experimental strategy in which embryos were first exposed to exogenous...
Topics
- Animals
- Antigens, CD
- Antigens, Differentiation, T-Lymphocyte
- CD57 Antigens
- Cell Adhesion Molecules, Neuronal
- Cell Movement
- Chick Embryo
- Culture Techniques
- Mesoderm
- Neural Crest
- Neural Tube Defects
