Article
Ectopic expression of Hoxa-1 in the zebrafish alters the fate of the mandibular arch neural crest and phenocopies a retinoic acid-induced phenotype.
Development (Cambridge, England) - 1 Mar 1996
Alexandre D, Clarke J D, Oxtoby E, Yan Y L, Jowett T, Holder N
Abstract excerpt
Considerable evidence has demonstrated that retinoic acid influences the formation of the primary body axis in vertebrates and that this may occur through the regulation of Hox gene expression. In this study, we show that the phenotype induced by exogenous retinoic acid in the zebrafish can also...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cloning, Molecular
- Gene Expression Regulation, Developmental
- Genes, Homeobox
- Homeodomain Proteins
- Mandible
- Molecular Sequence Data
- Neural Crest
- Phenotype