Article
Maternal obesity alters adiposity and monoamine function in genetically predisposed offspring.
American journal of physiology. Regulatory, integrative and comparative physiology - 1 Nov 2002
Levin Barry E, Dunn-Meynell Ambrose A
Abstract excerpt
The impact of maternal obesity on brain monoamine function in adult offspring of dams selectively bred to express diet-induced obesity (DIO) or diet resistance (DR) was assessed by making dams obese or lean during gestation and lactation. After 12 wk on chow and 4 wk on a 31% fat diet, offspring hypothalamic nucleus size and [(3)H]nisoxetine binding to norepinephrine transporters (NET) and [(3)H]paroxetine...
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