Article
Striatal dopamine metabolism is differentially affected by insulin according to the genotype in Zucker rats: a microdialysis study.
Psychoneuroendocrinology - 1 Oct 1992
Orosco M, Rouch C, Gripois D, Blouquit M F, Roffi J, Jacquot C, Cohen Y
Abstract excerpt
The genetically obese Zucker rat presents several abnormalities related to insulin and brain monoamines, which may play a role in its impaired regulation of food intake and body weight. In a previous study, the possible insulin-monoamine interplay was investigated by measuring brain monoamine and metabolite levels in the three genotypes of the Zucker strain. In addition to the expected results, insulin had a...
Topics
- 3,4-Dihydroxyphenylacetic Acid
- 5-Methoxytryptamine
- Animals
- Body Weight
- Corpus Striatum
- Dopamine
- Eating
- Female
- Genotype
- Homovanillic Acid
- Insulin