Article
Suppression of a mitochondrial point mutation in a tRNA gene can cast light on the mechanisms of 3' end-processing.
Current genetics - 1 May 1994
Rinaldi T, Francisci S, Zennaro E, Frontali L, Bolotin-Fukuhara M
Abstract excerpt
We used a genetic approach to study the nuclear factors involved in the biogenesis of mitochondrial tRNAs. A point mutation in the mitochondrial tRNA(Asp) gene of Saccharomyces cerevisiae had previously been shown to result in a temperature-sensitive respiratory-deficient phenotype as a result of...
Topics
- Base Sequence
- Diploidy
- Genes, Fungal
- Molecular Sequence Data
- Nucleic Acid Conformation
- Phenotype
- Point Mutation
- RNA
- RNA Processing, Post-Transcriptional
- RNA, Fungal
- RNA, Mitochondrial
- RNA, Transfer, Asp