Article
Allelic loss and somatic differentiation in human male germ cell tumors.
Oncogene - 1 Aug 1994
Murty V V, Bosl G J, Houldsworth J, Meyers M, Mukherjee A B, Reuter V, Chaganti R S
Abstract excerpt
The complex but poorly understood human male germ cell tumors offer unusual opportunities for the genetic analysis of malignant transformation and embryonal differentiation in a pluripotential stem cell lineage. Histologically, these tumors are divided into two major subgroups, seminomas which ar...
Topics
- Alleles
- Cell Differentiation
- Chromosome Deletion
- Genes, Tumor Suppressor
- Germinoma
- Humans
- Male
- Proto-Oncogene Proteins
- Proto-Oncogene Proteins c-kit
- Proto-Oncogenes
- Receptor Protein-Tyrosine Kinases
- Receptors, Colony-Stimulating Factor
