Article
Allelic loss and somatic differentiation in human male germ cell tumors.
Oncogene - 1 Aug 1994
Murty V V, Bosl G J, Houldsworth J, Meyers M, Mukherjee A B, Reuter V, Chaganti R S
Abstract excerpt
The complex but poorly understood human male germ cell tumors offer unusual opportunities for the genetic analysis of malignant transformation and embryonal differentiation in a pluripotential stem cell lineage. Histologically, these tumors are divided into two major subgroups, seminomas which are characterized by inability to express embryonal differentiation, and non-seminomas which are characterized by ability...
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