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Article

Teratomatous genotype detected in malignancies of a non-germ cell phenotype.

Laboratory investigation; a journal of technical methods and pathology - 1 Jan 2000

Devouassoux-Shisheboran M, Vortmeyer A O, Silver S A, Zhuang Z, Tavassoli F A

Abstract excerpt

Originating from post-meiotic germ cells, mature ovarian teratomas (MOT) are genetically homozygous tumors within heterozygous hosts. MOT may be associated with malignant tumors of a non-germ cell phenotype (so-called malignant transformation). Based on the presence of in situ changes, some cases have been hypothesized to arise from teratomatous tissue. However, other malignancies associated with mature...

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PMID: 10653006
DOI: 10.1038/labinvest.3780011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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