Article
Phenotypic mixing between different hepadnavirus nucleocapsid proteins reveals C protein dimerization to be cis preferential.
Journal of virology - 1 Aug 1994
Chang C, Zhou S, Ganem D, Standring D N
Abstract excerpt
Hepadnaviruses encode a single core (C) protein which assembles into a nucleocapsid containing the polymerase (P) protein and pregenomic RNA during viral replication in hepatocytes. We examined the ability of heterologous hepadnavirus C proteins to cross-oligomerize. Using a two-hybrid assay in HepG2 cells, we observed cross-oligomerization among the core proteins from hepatitis B virus (HBV), woodchuck hepatitis...
Topics
- Animals
- Base Sequence
- Capsid
- Cell Line
- Cross Reactions
- DNA, Viral
- Epitopes
- Hepatitis B Virus, Woodchuck
- Hepatitis B virus
- Liver
- Molecular Sequence Data
