Article
Mosaic particles formed by wild-type hepatitis B virus core protein and its deletion variants consist of both homo- and heterodimers.
FEBS letters - 14 Aug 2003
Kazaks Andris, Dishlers Andris, Pumpens Paul, Ulrich Rainer, Krüger Detlev H, Meisel Helga
Abstract excerpt
Co-expression in Escherichia coli of wild-type (wt) hepatitis B virus core protein (HBc) and its naturally occurring variants with deletions at amino acid positions 77-93 or 86-93 leads to formation of mosaic particles, which consist of three dimer subunit compositions. These compositions are wt/variant HBc heterodimers and two types of homodimers, formed by wt HBc or the variant HBc themselves. Mosaic particles...
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