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Article

Structure function relationships in diphtheria toxin channels: II. A residue responsible for the channel's dependence on trans pH.

The Journal of membrane biology - 1 Jan 1994

Mindell J A, Silverman J A, Collier R J, Finkelstein A

Abstract excerpt

Ion-conducting channels formed in lipid bilayers by diphtheria toxin are highly pH dependent. Among other properties, the channel's single channel conductance and selectivity depend on proton concentrations on either side of the membrane. We have previously shown that a 61 amino acid fragment of DT is sufficient to form a channel having the same pH-dependent single channel properties as that of the intact toxin....

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 7516433
DOI: 10.1007/BF00234996

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Structure function relationships in diphtheria toxin channels: II. A residue responsible for the channel's dependence on trans pH.PMID 7516433Read ↗

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