Article
Characterization of HIV-1 strains isolated from patients treated with TIBO R82913.
AIDS research and human retroviruses - 1 Jan 1994
Vandamme A M, Debyser Z, Pauwels R, De Vreese K, Goubau P, Youle M, Gazzard B, Stoffels P A, Cauwenbergh G F, Anne J
Abstract excerpt
The drug sensitivities of human immunodeficiency virus type 1 (HIV-1) isolates from a group of four untreated and seven TIBO R82913-treated patients were determined in a reverse transcriptase (RT) assay. Five of the treated patients harbored HIV-1 isolates with R82913 sensitivity comparable to th...
Topics
- Acquired Immunodeficiency Syndrome
- Amino Acid Sequence
- Base Sequence
- Benzodiazepines
- Cells, Cultured
- DNA Primers
- Drug Resistance, Microbial
- Genetic Variation
- HIV Reverse Transcriptase
- HIV-1
- Humans
- Imidazoles
- Molecular Sequence Data
- RNA-Directed DNA Polymerase
- Reverse Transcriptase Inhibitors
- Sequence Alignment